The Weekly Epidemiological Report (WER) for 23 February 2018 contains an updated position paper replacing the 2004 World Health Organization (WHO) position paper on Bacille Calmette-Guérin (BCG) vaccine and the 2007 WHO revised BCG vaccination guidelines for infants at risk for HIV infection. It incorporates recent developments in the field of tuberculosis, provides revised guidance on the immunisation of children infected with HIV, and re-emphasises the importance of the BCG birth dose. This position paper also includes recommendations on the use of BCG for the prevention of leprosy. Recommendations on the use of BCG vaccines were discussed by SAGE in October 2017. Evidence presented at the meeting has been published by the WHO.